Protects the healthy cells from the effects of methotrexate while allowing methotrexate to enter and kill cancer cells.Ī “chemoprotectant” drug that reduces the undesired effects of certain chemotherapy drugs.Ĭhemical producing severe methemoglobinemia. Used in combination with vasodilator phentolamine or nitroprusside to prevent local thrombosis and ischemia.įorms cyanocobalamin, a non-toxic metabolite that is easily excreted through the kidneys. Reverses hypercoagulable state by interacting with antithrombin III. Stimulates the formation of adenyl cyclase causing intracellular increase in cycling AMP and enhanced glycogenolysis and elevated serum glucose concentration.ĭextrose (the monosaccharide glucose) is used, distributed and stored by body tissues and is metabolized to carbon dioxide and water with the release of energy. This enzyme plays a key role in the metabolism of ethylene glycol and methanol.īeta blockers and calcium channel blockers

Reverses the effects of benzodiazepines by competitive inhibition at the benzodiazepine binding site on the GABA A receptor.Ī competitive inhibitor of the enzyme alcohol dehydrogenase found in the liver. Not known partial protection against acute hepatic failure may displace amatoxin from protein-binding sites allowing increased renal excretion may also inhibit penetration of amatoxin to hepatocytes.ĭeferoxamine acts by binding free iron in the bloodstream and enhancing its elimination in the urine.īinds molecules of digoxin, making them unavailable for binding at their site of action on cells in the body.Ĭhelation of lead ions and endogenous metals (e.g., zinc, manganese, iron, copper).Ī potent antagonist to acetylcholine in muscarinic receptors. Interrupts the entero-hepatic cycle with multiple dose.Īlbuterol inhaler, insulin & glucose, NaHCO 3, kayexalateĬompetitive inhibition of muscarinic receptors. Non-specific poisons except cyanide, iron, lithium, caustics and alcohol.Ībsorption of drug in the gastric and intestinal tracts. Restores depleted glutathione stores and protects against renal and hepatic failure. The following are antidotes that should be familiarized by the nurse to respond to this emergency situation quickly. This post will help you familiarize yourself with the common antidotes that are used in the hospital setting.

The term antidote is a Greek word meaning “given against”. An antidote is a substance that can counteract a form of poisoning.

Diazepam antidote